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The Brain Boss Nutrients

What makes Brain Boss so effective is how nutrient-dense it is and the blend of key vitamins, amino acids and other nutrients that work together to boost cognitive performance and support brain health. You might be thinking, “Okay, great, but what does that mean for me?” Well, if you have ever had an unproductive day, lost hours or even days of the week struggling to focus, get important things done, or feeling burnt out and procrastinating, Brain Boss can help. How can Brain Boss help?


Brain Boss contains the full spectrum of essential B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) as well as vitamin D and zinc which are vital nutrients for the proper functioning of both the brain and body. The B vitamins and zinc aid in the metabolism of proteins, carbohydrates and fats to produce vital energy for the body. Both support brain health and are a factor in the maintenance of good health. Vitamin D supports mood and is also a factor in the maintenance of good health.[1][2][3][4][5][6][7][8]

Brain Boss also has nutrients such as inositol which supports mood and is essential for brain and nervous system health.[9][10] It also has choline bitartrate which supports healthy nerve transmission, liver function and brain health.[3][5][6][11] In addition, Brain Boss also contains milk thistle (supports healthy liver function, supports immune function, promotes antioxidant activity),[12][13][14][15][16][17] Rhodiola rosea (supports cognitive function, focus, mental stamina and provides anti-stress and mood support),[18][19][20][21] acetyl-L-carnitine (provides memory support, fat metabolism, enhanced cognitive function and brain health support),[22][23][24][25][26][27][28][29][30] and L-tyrosine (provides anti-stress and mental alertness support).[31][32][33][34][35][36]

To improve the effectiveness of the caffeine content and remove the jittery effects and crash, Brain Boss contains L-theanine (provides relaxation support and focus)[37][38][39] alongside the caffeine (provides energy, boosts metabolism, promotes endurance, supports enhanced cognitive performance, focus and alertness).[40][41][42][43][44][45]

With such an extensive list of benefits for you, it isn’t a surprise that Brain Boss is the smart and healthy choice for cognitive performance and brain health support; combining all these nutrients and benefits into a potent, compact package (1.93 fl oz bottle) with zero sugar that is ready-made to consume. Brain Boss is manufactured in a certified GMP facility located in the U.S.A. to ensure quality, purity and potency.

Brain Boss contains nutrients that can be consumed through food sources which makes Brain Boss a healthier alternative to coffee, tea, and energy supplements. We’ve listed some the food sources these nutrients can be consumed from below.

Foods That Contain The Nutrients Found In Brain Boss:

Vitamin B1

Vitamin B2

Vitamin B3

Vitamin B5

Vitamin B6

Vitamin B7

Vitamin B12

Folic Acid

Choline Bitartrate


Vitamin D


Acetyl L-Carnitine




Milk Thistle

Rhodiola Rosea



  1.       Sechi G, et al. Advances in clinical determinants and neurological manifestations of B vitamin deficiency in adults. Nutr Rev. 2016
  2.       Köbe T, et al. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. Am J Clin Nutr. (2016)
  3.       Shils ME, Olson JA, Shike M, Ross AC, Caballero B, Cousins RJ, editors. Modern Nutrition in Health and Disease, 10th edition. Philadelphia (PA): Lippincott Williams & Wilkins; 2006.
  4.       Groff J, Gropper S. Advanced Nutrition and Human Metabolism, 3rd edition. Belmont (CA): Wadsworth/Thomson Learning; 2000.
  5.       IOM 1998: Institute of Medicine. Panel on Folate, other B Vitamins, and Choline and Subcommittee on Upper Reference Levels of Nutrients, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin and Choline. Washington (DC): National Academies Press; 1998.
  6.       IOM 2006: Institute of Medicine. Otten JJ, Pitzi Hellwig J, Meyers LD, editors. Institute of Medicine. Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. Washington (DC): National Academies Press; 2006.
  7.       Berk M, Sanders KM, Pasco JA, Jacka FN, Williams LJ, Hayles AL, Dodd S. Vitamin D deficiency may play a role in depression. Medical Hypotheses. 2007;69:1316–1319.
  8.       Zhao, Christine E. Tinberg, Stephen J. Lippard, James O. McNamara. Vesicular Zinc Promotes Presynaptic and Inhibits Postsynaptic Long-Term Potentiation of Mossy Fiber-CA3 Synapse. Neuron, 2011; 71 (6): 1116 DOI: 10.1016/j.neuron.2011.07.019
  9.       Levine J, et al. Double-blind, controlled trial of inositol treatment of depression. Am J Psychiatry. (1995)
  10.   Levine J, et al. Follow-up and relapse analysis of an inositol study of depression. Isr J Psychiatry Relat Sci. (1995)
  11.   Aslan E, et al. Cdp-choline and Its Endogenous Metabolites, Cytidine and Choline, Promote the Nerve Regeneration and Improve the Functional Recovery of Injured Rat Sciatic Nerves. Neurological Research. (2011)
  12.   Bradley PR, editor. 2006. British Herbal Compendium: A Handbook of Scientific Information on Widely Used Plant Drugs, Volume 2. Bournemouth (UK): British Herbal Medicine Association.
  13.   Hoffmann D. 2003. Medical Herbalism: The Science and Practice of Herbal Medicine. Rochester (VT): Healing Arts Press.
  14.   Blumenthal M, Goldberg A, Brinkmann J, editors. 2000. Herbal Medicine: Expanded Commission E Monographs. Boston (MA): Integrative Medicine Communications.
  15.   Mills S, Bone K. 2000. Principles and Practice of Phytotherapy. Toronto (ON): Churchill Livingstone.
  16.   Wilasrusmee C, et al. Immunostimulatory effect of Silybum Marianum (milk thistle) extract. Med Sci Monit. (2002)
  17.   Asghar Z, et al. Evaluation of antioxidant properties of silymarin and its potential to inhibit peroxyl radicals in vitro. Pak J Pharm Sci. (2008)
  18.   Olsson, E.M.G., von Schéele, B., Panossian, A.G., 2009. A randomized double-blind placebo controlled parallel group study of SHR-5 extract of Rhodiola rosea roots as treatment for patients with stress related fatigue. Planta medica 75,105-112.
  19.   Winston D, Maimes S. Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Rochester (VT): Healing Arts Press, 2007.
  20.   Pizzorno JE, Murray MT, editors. Textbook of Natural Medicine. Third edition, volume 1. St. Louis (MI): Churchill Livingstone Elsevier; 2006.
  21.   Hoffmann D. Medical Herbalism: The Science and Practice of Herbal Medicine. Rochester (VT): Healing Arts Press; 2003.
  22.   Malaguarnera M, et al. Serum Carnitine Levels in Centenarians. Clinical Drug Investigation. (1999)
  23.   Malaguarnera M, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr. (2007)
  24.   Pistone G, et al. Levocarnitine administration in elderly subjects with rapid muscle fatigue: effect on body composition, lipid profile and fatigue. Drugs Aging. (2003)
  25.   Salvioli G, et al. L-acetylcarnitine treatment of mental decline in the elderly. Drugs Exp Clin Res. (1994)
  26.   Nasca C, et al. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proc Natl Acad Sci U S A. (2013)
  27.   Kuratsune H, et al. Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain. Neuroimage. (2002)
  28.   Wutzke KD, Lorenz H. The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects. Metabolism. 2004 Aug;53(8):1002-6.
  29.   Müller DM, Seim H, Kiess W, Löster H, Richter T. Effects of oral L-carnitine supplementation on in vivo long-chain fatty acid oxidation in healthy adults. Metabolism. 2002 Nov;51(11):1389-91.
  30.   Wall BT, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans: the dual role of muscle carnitine in exercise metabolism. J Physiol. 2011 Jan 4.
  31.   Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR. Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiology and Behavior 2007;92(4):575-582.
  32.   O'Brien C, Mahoney C, Tharion WJ, Sils IV, Castellani JW. Dietary tyrosine benefits cognitive and psychomotor performance during body cooling. Physiology & Behavior 2007;90(2-3):301-307.
  33.   Magill RA, Waters WF, Bray GA, Volaufova J, Smith SR, Lieberman HR, McNevin N, Ryan DH. Effects of tyrosine, phentermine, caffeine d-amphetamine, and placebo on cognitive and motor performance deficits during sleep deprivation. Nutritional Neuroscience 2003;6(4):237-246.
  34.   Thomas JR, Lockwood PA, Singh A, Deuster PA. Tyrosine improves working memory in a multitasking environment. Pharmacology, Biochemistry and Behavior 1999;64(3):495-500.
  35.   Dollins AB, Krock LP, Storm WF, Wurtman RJ, Lieberman HR L-tyrosine ameliorates some effects of lower body negative pressure stress. Physiology and Behavior 1995;57(2):223-230
  36.   Neri DF, Wiegmann D, Stanny RR, Shappell SA, McCardie A, McKay DL. The effect of tyrosine on cognitive performance during extended wakefulness. Aviation, space, and environmental medicine 1995;66(4);313-319.
  37.   Nobre AC, Rao A, Owen GN. 2008. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition 17(Suppl1):167-168
  38.   Kimura K, Ozeki M, Juneja LR, Ohira H. 2007. L-Theanine reduces psychological and physiological stress responses. Biological Psychology 74(1):39-45
  39.   Lu K, Gray MA, Oliver C, Liley DT, Harrison BJ, Bartholomeusz CF, Phan KL, Nathan PJ. 2004. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Human Psychopharmacology 19(7):457-65
  40.   Christopher G, Sutherland D, Smith A. Effects of caffeine in non-withdrawn volunteers. Human Psychopharmacology 2005;20(1):47-53.
  41.   Kamimori GH, Penetar DM, Headley DB, Thorne DR, Otterstetter R, Belenky G. Effect of three caffeine doses on plasma catecholamines and alertness during prolonged wakefulness. European Journal of Clinical Pharmacology 2000;56(8):537-544.
  42.   Zwyghuizen-Doorenbos A, Roehrs TA, Lipschutz L, Timms V, Roth T. Effects of caffeine on alertness. Psychopharmacology 1990;100(1):36-39.
  43.   Philip P, Taillard J, Moore N, Delord S, Valtat C, Sagaspe P, Bioulac B. The effects of coffee and napping on night time highway driving: a randomized trial. Annals of Internal Medicine 2006;144(11):785-791.
  44.   Doherty M, Smith PM. Effects of caffeine ingestion on rating of perceived exertion during and after exercise: a meta-analysis. Scandinavian Journal of Medicine & Science in Sports 2005;15(2):69-78.
  45.    Smith A, Sutherland D, Christopher G. Effects of repeated doses of caffeine on mood and performance of alert and fatigued volunteers. Journal of Psychopharmacology 2005;19(6):620-626.